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Nucleophilic displacement reactions are a type of substitution reaction where one nucleophile displaces a leaving group to create two new bonds with the substrate.

This is accomplished through three different types of nucleophilic displacement reactions: S1, E1 and E2.

Nucleophilic Displacement Reactions: S, E and E! S-Type Nucleophilic Displacement Reaction .

The first type of nucleophile displacement reaction is the S-Type.

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This mechanism involves an alcohol reacting with a ketone to form an ester in one step.

In this mechanism you will need at least two more reagents for activation (acid or base) .

That are used before adding your nucleophile as shown below.

The key aspect of these reactions is based on how much water needs to be present relative to the amount of acid needed.

Because it affects the equilibrium position where both reactants and products exist together in solution.

 

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